Metronidazole material supplier low price CAS NO.443-48-1
- FOB Price: USD: 23.00-30.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Available Specifications:
99%(1-25)Kilogram99%(26-50)Kilogram99%(51-100)Kilogram
- Product Details
Keywords
- Metronidazole supplier
- Bexon
- Flagyl
Quick Details
- ProName: Metronidazole material supplier low pr...
- CasNo: 443-48-1
- Molecular Formula: C6H9N3O3
- Appearance: white powder
- Application: antibacterial medicine
- DeliveryTime: 3-7 days
- PackAge: 25kg/drum
- Port: CMP
- ProductionCapacity: 100 Kilogram/Week
- Purity: 99%
- Storage: Dry and cold condition
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
- Related Substances: N/A
- Heavy Metal: 20ppm max
- Valid Period: 4 years
- MW: 171.15
- EINECS: 207-136-1
- Melting point: 159-161 °C
- density: 1.3994
- HS Code: 29332990
- Hazard Class: 6.1
Superiority
Quality & Price
1. Factory price, reliable quality
2. Advanced technology and equipments, strong R&D ability
3. Years produce and exporting experience
4. Strict quality control, free sample for test before order, keep sample after shipment for further issue
Service
1. Enough stock, fast shipment, professional team to deal with it
2. Different packing can be customized, photos available before shipment
3. Quick response for all inquiries or claims
Wuhan Xinru Chemical has several stock-holding factories, based on strong R&D ability, advanced
production technology and experienced team; pluses international trade office in Wuhan, we
can offer high and stable quality products with quick response and service.
Please contact us freely for more details about products specification, packing method, price term,
lead time, payment term and any other information, we would try our best to satisfy you both on quality
and price as much as we can.
Details
Metronidazole
CAS: 443-48-1
Purity: 99%
Pharmacology and mechanism of action
Metronidazole is a 5-nitroimidazole derivative which was originally introduced against Trichomonas
vaginalis in 1960. Soon it was shown to possess a broad spectrum of activity against other protozoal
infections such as amoebiasis and giardiasis, and more recently against infections due to anaerobic
bacteria . The mechanism of action of metronidazole is not well understood. In the parasite, the 5-nitro
group of the drug undergoes reductive transformation to a cytotoxic intermediate which binds to the
helical structure of the DNA leading to strand breakage and eventual cell death.
Indications and Usage
Metronidazole is a nitroimidazole antibiotic, also known as metronidazol and novonidazol. It was initially
used to treat vaginal trichomaniasis, with very significant clinical effects. It is broadly used to prevent and
treat oral anaerobic infections.
In hospitals, it has been used frequently to prevent and treat respiratory, gastrointestinal, peritoneal, pelvic,
skin, soft tissue, joint, and brain infections, cardiomyitis, and septicemia caused by anaerobic bacteria. The
effectiveness of Metronidazole towards treating body tissue and intestinal amoebiasis is significant, and it
the preferred drug to treat parasitosis.
Side effects
Side effects with doses used to treat protozoal infections are usually mild, reversible and self-limiting and
may affect 4% to 5% of treated patients. The most common are gastrointestinal disturbances (nausea,
vomiting, epigastric pain, metallic taste, furring of the tongue), intolerance to alcohol (disulfiram-like effect)
and central nervous system effects (headache, dizziness and sleepiness) . Other side effects reported
include urticaria, darkening of the urine with a reddish-brown discoloration and transient neutropenia .
During prolonged high doses, the drug may cause severe neurotoxic side effects such as peripheral
neuropathy, paraesthesia and epileptiform seizures . Few case reports of bone marrow depression,
gynecomastia and acute pancreatitis have been reported. Although metronidazole is mutagenic in
bacteria and carcinogenic in rodents, no association with human cancer has been proven .
Package
25KG/drum
1kg/foil bag
Storage
2-8°C
Related pictures
Wuhan Xinru Chemical Industry Co.,Ltd founded in 2006, engaged in R&D, producing
and marketing barium salts, sodium salts, fertilizer and pharmaceutical intermediates.
Xinru Chemical has several stock-holding factories, based on strong R&D ability, advanced
production technology and experienced team; pluses international trade office in Wuhan, we
can offer high and stable quality products with quick response and service.
From 2006,we have already developed and established a very good relationship with different
reputed customers in EU, Egypt, Canada, Korea, USA, Chile, Turkey, Thailand etc.Our products
widely used in water purification,magnet material, rubber, ceramic,glass,painting, powder coating,
plastic industry, pharmacy and so on.